Energy Restriction, Aging, and Influenza Infection

Energy restriction (ER) without malnutrition has been found to prolong lifespan in mice and delay age-related changes in immunity. However, aged (22 mo old) ER mice showed increased mortality, inhibited viral clearance, and decreased natural killer (NK) cell cytotoxicity after influenza A virus (H1N1, PR8) infection, in comparison with aged mice that consumed food ad [...] http://digg.com/u12lS0