Inflammation Database: genes involved in inflammation: ABCB1 – ACP5

ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), member 1)

[ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-GP, PGY1]

In inflamed intestinal epithelium (IE) of patients with gastrointestinal disorders, MDR1 expression is significantly lower (Blokzijl et al., 2007). Reduced MDR1 levels may aggravate inflammation in the intestines.

Related diseases: Crohn’s disease (CD), ulcerative colitis (UC), diverticulitis, collagenous colitis.

Reference:

Blokzijl, H., Vander Borght, [...] http://digg.com/u1Nsjb