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Depression Database: Genetic Factors: Transporters: SLCO1C1 (solute carrier organic anion transporter family, member 1C1)

SLCO1C1 (solute carrier organic anion transporter family, member 1C1)

Other Symbols:

OATP-F, OATP1, OATP1C1, OATPRP5, SLC21A14

Disease relevance:

This gene belongs to the organic anion transporter family. It is a thyroid hormone transporter found at the blood-brain barrier. Polymorphisms in the gene, especially OATP1C1-intron3C > T and the OATP1C1-C3035T, are related [...] http://digg.com/u1Ujew

Depression Database: Genetic Factors: Transporters: SLC6A4 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 4)

SLC6A4 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 4)

Other Symbols:

5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, hSERT

1) Disease relevance:

This gene belongs to the sodium:neurotransmitter symporter family and is incharge of transporting the neurotransmitter serotonin from synaptic spaces to presynaptic neurons. It is an important regulator of the serotonergic [...] http://digg.com/u1UXwT

Depression Database: Genetic Factors: Transporters: SLC6A3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3)

SLC6A3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3)

Other Symbols:

DAT, DAT1

1) Disease relevance:

This gene is a dopamine transporter. It belongs to the sodium- and chloride-dependent neurotransmitter transporter family. Variations in the gene are linked to idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, and susceptibility to [...] http://digg.com/u1UHxc

Depression Database: Genetic Factors: Transporters: SLC6A2 (solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2)

SLC6A2 (solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2)

Other Symbols:

NAT1, NET, NET1, SLC6A5

Disease relevance:

This gene is a member of the sodium:neurotransmitter symporter family. It is involved in the regulation of norepinephrine homeostasis and central nervous monoaminergic homeostasis. It is one of the primary targets of many antidepressants. Dysfunction [...] http://digg.com/u1UE85

Depression Database: Genetic Factors: Transporters: ABCA13 (ATP-binding cassette, sub-family A (ABC1), member 13)

ABCA13 (ATP-binding cassette, sub-family A (ABC1), member 13)

Other Symbols:

DKFZp313D2411, FLJ16398, FLJ33876, FLJ33951

Disease relevance:

This gene is belongs to the ABC gene subfamily A (ABCA) and is a lipid transporter gene. It is found to be a candidate gene in schizophrenia, bipolar disorder, and depression (Knight et al., 2009).

Sample size:

100 cases with [...] http://digg.com/u1TsiZ